Specific protein degradation is getting explored instead strategy in cancer, whereby the natural protein degradation system is co-opted for therapeutic purposes. A short while ago created novel molecules known as proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules with two ligands joined by a linker. One particular ligand binds into the ‘protein https://www.directivepublications.org/journal-of-clinical-breast-cancer/