Steroids are hormones that occur naturally in the body. Steroid medicines are man-made and are similar to the natural hormones made in the body. An acute exacerbation is more commonly known bey a 'flare-up'. An acute exacerbation of chronic obstructive pulmonary disease (COPD) is a sudden worsening of COPD symptoms https://www.webwiki.it/tr.wikipedia.org/wiki/Vitamin