2. Histamine Receptor Antagonism: Some sedatives, including antihistamines, exert their sedative effects by blocking histamine receptors from the brain, particularly H1 receptors. Histamine performs a role in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness. Sufficient and properly-controlled experiments have did not demonstrate a possibility for https://sedatives-drugs75318.isblog.net/understanding-sedatives-drugs-complete-breakdown-50229808