Pentobarbital will decrease the level or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of meloxicam by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of aripiprazole by affecting hepatic/intestinal en... https://bookmarkize.com/story20330012/the-ultimate-guide-to-pentobarbital-de-sodium